University Assistant Professor


"Life is nothing but an electron looking for a place to rest"  
- Albert Szent-Györgyi (Nobel Laureate in Physiology 1937)

Current research

My team's goal is to develop smart bio-hybrid approaches that can help to probe or re-wire the bioenergetics of living systems. These can serve as platforms to launch new biotechnologies to address a range of societal needs, including for renewable energy generation, carbon recycling, precision farming, environmental sensing, and treating pathogenic biofilms. Currently, we are focused on understanding and re-wiring photosynthesis towards sustainable energy conversion. We work at the intersection of many disciplines, including physics, synthetic biology, chemical biology, engineering and material science; but at the heart of our work is electrochemistry.

Please see our website for more info: https://www.ch.cam.ac.uk/group/zhang

Jenny completed her PhD in bioinorganic chemistry at the University of Sydney, Australia, with a brief stint at the Hebrew University of Jerusalem. During this time, she developed redox active platinum-based anti-cancer agents and studied their biodistribtion and metabolism within tumour models. Following this, she was awarded a Marie Curie Incoming International Fellowship at the University of Cambridge to explore how biocatalysts can be exploited to generate solar fuels. In particular, she worked on developing strategies to re-wire complex enzymes, such as the water-oxidation enzyme photosystem II, to electrodes/semiconductors/other proteins in an emerging field known as 'semi-artificial photosynthesis'. She has since been awarded a BBSRC David Phillips Fellowship, followed by appointment to Assistant Professor in Materials Chemistry at the Yusuf Hamied Department of Chemistry. She will become Professor in Bioenergetics and Materials Chemistry in October 2026, where she then heads the BEAM Team. Presently, her team takes on re-wiring biology to another level of complexity - in living cells! 

Jenny was awarded the RSC Felix Franks Biotechnology Medal in 2022 and the L'Oreal UNESCO Sustainable Development award for Women in Science in 2023. She was recently awarded the Outstanding Supervisor Award by her department, and the Luigi Galvani Prize by the International Bioelectrochemical Society in 2026.

Dr Zhang discusses her research

Publications

Quantitative measurement of the reduction of platinum(IV) complexes using X-ray absorption near-edge spectroscopy (XANES).
MD Hall, HL Daly, JZ Zhang, M Zhang, RA Alderden, D Pursche, GJ Foran, TW Hambley
Metallomics : integrated biometal science
(2012)
4
Pt(IV) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate.
JZ Zhang, E Wexselblatt, TW Hambley, D Gibson
Chemical Communications
(2011)
48
U.S. Food and Drug Administration approval: ofatumumab for the treatment of patients with chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab.
SJ Lemery, J Zhang, MD Rothmann, J Yang, J Earp, H Zhao, A McDougal, A Pilaro, R Chiang, JE Gootenberg, P Keegan, R Pazdur
Clinical cancer research : an official journal of the American Association for Cancer Research
(2010)
16
Fluorescent analogues of quinoline reveal amine ligand loss from cis and trans platinum(II) complexes in cancer cells.
EJ New, C Roche, R Madawala, JZ Zhang, TW Hambley
J Inorg Biochem
(2009)
103
Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: the effect of charge on drug distribution in solid tumour models.
NS Bryce, JZ Zhang, RM Whan, N Yamamoto, TW Hambley
Chemical communications (Cambridge, England)
(2009)
8
Investigations using fluorescent ligands to monitor platinum( iv ) reduction and platinum( ii ) reactions in cancer cells
EJ New, R Duan, JZ Zhang, TW Hambley
Dalton Transactions
(2009)
Platinum Anticancer Drugs, Chemical Biology of
J Zhang, R Whan, T Hambley
(2008)

Research Interest Groups

Telephone number

01223 336426

Email address

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