The Zhang Group

Laura Wey

Research Assistant

I am a PhD student working with the Zhang group and based in the Howe group in the Department of Biochemistry.

Background

Bachelor of Philosophy (an undergraduate science research degree) with First Class Honours in Biology, Australian National University, Australia (2011-2015)
Research Assistant in the Price Lab, Research School of Biology at the Australian National University & ARC Centre of Excellence for Translational Photosynthesis (2016-2017)

Research

I am interested in the biochemistry of photosynthesis, in particular pathways of electron transfer. I mainly work with the model photosynthetic cyanobacterium (also known as blue-green algae) Synechocystis sp. PCC 6803. 
I aim to understand more of the biological factors underpinning cyanobacteria's ability to export electrons to their environment, called exoelectrogenic activity (Lea-Smith et al., 2016). There is great potential to harness cyanobacteria's exoelectrogenic activity in biophotovoltaic devices to generate renewable electricity (McCormick et al., 2015).

Funding

Cambridge International Scholarship from the Cambridge Commonwealth, European & International Trust. 

Publications

Elucidating the bio-electrochemical mechanism of exoelectrogenesis of the cyanobacterium Synechocystis sp. PCC6803
L Wey
(2021)
(doi: 10.17863/CAM.79424)
A biophotoelectrochemical approach to unravelling the role of cyanobacterial cell structures in exoelectrogenesis
LT Wey, JM Lawrence, X Chen, R Clark, DJ Lea-Smith, JZ Zhang, CJ Howe
Electrochimica Acta
(2021)
395
(doi: 10.1016/j.electacta.2021.139214)
A modular toolset for electrogenetics
JM Lawrence, Y Yin, P Bombelli, A Scarampi, M Storch, LT Wey, A Climent-Catala, PixCell iGEM team, GS Baldwin, D O’Hare, CJ Howe, JZ Zhang, TE Ouldridge, R Ledesma-Amaro
(2021)
(doi: 10.1101/2021.09.10.459750)
A biophotoelectrochemical approach to unravelling the role of cyanobacterial cell structures in exoelectrogenesis
L Wey, J Lawrence, X Chen, R Clark, D Lea-Smith, J Zhang, C Howe
(2021)
(doi: 10.1101/2021.04.01.437897)
Phenazines as model low-midpoint potential electron shuttles for photosynthetic bioelectrochemical systems
ER Clifford, RW Bradley, LT Wey, JM Lawrence, X Chen, CJ Howe, JZ Zhang
Chem Sci
(2021)
12
(doi: 10.1039/d0sc05655c)
Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001
JA Kaczmarski, N-S Hong, B Mukherjee, LT Wey, L Rourke, B Förster, TS Peat, GD Price, CJ Jackson
Biochemistry
(2019)
58
(doi: 10.1021/acs.biochem.9b00880)
Cover Feature: The Development of Biophotovoltaic Systems for Power Generation and Biological Analysis (ChemElectroChem 21/2019)
LT Wey, P Bombelli, X Chen, JM Lawrence, CM Rabideau, SJL Rowden, JZ Zhang, CJ Howe
ChemElectroChem
(2019)
6
(doi: 10.1002/celc.201901663)
The Development of Biophotovoltaic Systems for Power Generation and Biological Analysis
LT Wey, P Bombelli, X Chen, JM Lawrence, CM Rabideau, SJL Rowden, JZ Zhang, CJ Howe
Chemelectrochem
(2019)
6
(doi: 10.1002/celc.201900997)
Structural basis for the allosteric regulation of the SbtA bicarbonate transporter by the PII-like protein, SbtB, fromCyanobiumsp. PCC7001
J Kaczmarski, N-S Hong, B Mukherjee, L Wey, L Rourke, B Förster, T Peat, D Price, C Jackson
(2019)
(doi: 10.1101/762807)
A neural classification method for supporting the creation of BioVerbNet.
HW Chiu, O Majewska, S Pyysalo, L Wey, U Stenius, AL Korhonen, M Palmer
J Biomed Semantics
(2019)
10
(doi: 10.1186/s13326-018-0193-x)

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